What do probiotics do?

Probiotics are live beneficial microorganisms that support healthy gut flora balance. Clinical evidence supports their use for reducing antibiotic-associated diarrhea, improving IBS symptoms, supporting intestinal barrier integrity, and modulating immune function.

When should I take probiotics?

Probiotics can be taken at any time, but taking them with or just before a meal may improve survival through stomach acid. Consistency matters more than timing — taking them daily at the same time helps establish routine.

What does 40 billion CFU mean?

CFU stands for Colony Forming Units — it measures the number of viable probiotic organisms per serving. 40 billion CFU is a clinically relevant dose studied in multiple trials. Higher CFU counts are not always better — strain specificity and viability matter more.

Should I take probiotics with antibiotics?

Many healthcare providers recommend taking probiotics during and after antibiotic courses to help restore healthy gut flora. Take probiotics at least 2 hours apart from antibiotic doses to avoid the antibiotic reducing probiotic viability.

How long should I take probiotics?

For general gut health maintenance, daily ongoing use is common. For specific situations like antibiotic recovery, 2-4 weeks post-antibiotic course is a typical protocol. Consult your healthcare provider for personalized guidance.

Probiotic 40 Billion CFU with Prebiotics | 4-Strain Daily Probiotic

Probiotic 40 Billion with Prebiotics

Prolean Wellness

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Probiotic 40 Billion with Prebiotics is a dietary supplement delivering a blend of four probiotic strains — Lactobacillus Acidophilus, Bifidobacter... Read Description ↓

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Description & Science

Probiotic 40 Billion with Prebiotics is a dietary supplement delivering a blend of four probiotic strains — Lactobacillus Acidophilus, Bifidobacterium Lactis, Lactobacillus Plantarum, and Lactobacillus Paracasei — commonly included in daily supplement formulations. This formula incorporates prebiotic Fructooligosaccharides and MAKTREK® Bi-Pass Technology, a marine polysaccharide complex designed to support probiotic delivery through the digestive system.*

Formulated for adults looking to incorporate a multi-strain probiotic and prebiotic blend into their daily routine as part of a balanced diet and healthy lifestyle.

Ingredients: Proprietary Blend of Probiotic Bacteria: MAKTREK® (Bi-Pass Technology), Lactobacillus Acidophilus, Bifidobacterium Lactis, Lactobacillus Plantarum, Lactobacillus Paracasei, Marine Polysaccharide Complex, Fructooligosaccharide, Hypromellose (vegetable capsule), Rice Maltodextrin, L-Leucine.
Manufacturer's country: USA
Product amount: 60 capsules / 113 g
Suggested use: Take two (2) capsules once daily as a dietary supplement.
Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.

📖 Read our clinical research guide: Probiotics — Why Your Gut and Mouth Both Need Them →

Part of Prolean Wellness's physician-curated supplement line — selected by our clinical team for quality, purity, and evidence-based formulation.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Ingredients

Proprietary Blend of Probiotic Bacteria (40 Billion CFU): MAKTREK® (Bi-Pass Technology), Lactobacillus Acidophilus, Bifidobacterium Lactis, Lactobacillus Plantarum, Lactobacillus Paracasei.
Prebiotic & Delivery Complex: Marine Polysaccharide Complex, Fructooligosaccharide.
Other Ingredients: Hypromellose (vegetable capsule), Rice Maltodextrin, L-Leucine.

Suggested Use

As a dietary supplement, adults take two (2) capsules once a day. For optimal results, split the dose by taking one (1) capsule during the day and one (1) capsule in the evening. Do not exceed two capsules per day.

Clinical Cautions

Do not exceed the recommended daily dose. If you are pregnant, nursing, taking any medications, or have an underlying medical condition, consult your physician before use.
KEEP OUT OF REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.

Targeted Health Systems

Microbiome Diversity & Gut Barrier Support
Delivers a potent 40 Billion CFU dose of four clinically studied probiotic strains to help replenish beneficial bacteria and support a healthy intestinal ecosystem.
Targeted Acid-Resistant Delivery
Utilizes patented MAKTREK® Bi-Pass Technology and a marine polysaccharide complex to protect the live bacteria from harsh stomach acid, ensuring safe passage to the deep GI tract.
Prebiotic Enrichment & Nutrient Metabolism
Infused with fructooligosaccharides (FOS) to act as a vital food source that nourishes beneficial microbes, supporting a normal, healthy metabolic response.

Frequently Asked Questions

What is MAKTREK® Bi-Pass Technology, and why does it matter?
Many standard probiotics are destroyed by harsh stomach acids before they ever reach your intestines. MAKTREK® Bi-Pass Technology is a patented, natural delivery system that forms a protective shield around the bacteria. This allows the probiotic strains to bypass stomach acids safely and release directly into your lower digestive tract where they are needed most.

Why is it recommended to split the daily dose into two parts?
Taking one capsule during the day and one capsule in the evening ensures a consistent, steady influx of beneficial bacteria into your gut microbiome over a full 24-hour cycle, maximizing the supplement's efficiency.

Does this product require refrigeration?
No. This formula is manufactured using stable, robust strains designed to maintain potency at room temperature. However, to preserve the maximum lifespan of the 40 Billion live cultures, it should be stored in a cool, dry place away from direct sunlight and tightly sealed after each use.